Microdosing
https://www.woz.ch/1818/microdosing/was-vom-trip-uebrig-bleibt
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[James Fadiman]
Dr. James Fadiman the world's leading authority
on psychedelic microdosing.
Examining the effects of administering
psychedelic drugs like LSD
and psilocybin
in amounts so small that they are below the perceptual threshold. As part of an
ongoing research project, Fadiman is collecting the self-reported testimonies
of hundreds of people from around the globe who have experimented with
psychedelic “microdosing” to treat ailments from anxiety to attention deficit
hyperactivity disorder, or simply to improve productivity or break through
writer’s block.
How does one microdose? You take a very small
dose of either LSD or psilocybin (roughly one-tenth to one-fifth of a normal
dose), on a regular schedule.
Fadiman recommends dosing in the morning, once
every three days. The dose isn’t enough to “trip,” but for some users, it can
lead to subtle yet profound internal shifts. Many microdosers report
experiencing improvements in mood; enhanced focus, productivity or creativity;
less reactivity; and in some cases, even relief from depression or cluster
headaches.
“What it seems to do is rebalance people,”
Fadiman told The Huffington Post.
HuffPost Science recently sat down with Fadiman
to learn more about how microdosing works and its potential for enhancing
well-being and treating a range of health problems.
Where did this idea of microdosing come from?
Dr. Albert Hofmann (the Swiss chemist who
discovered LSD)
had been microdosing for at least the last couple decades of his life. He lived
to be 102 and at age 100
he was still giving two-hour lectures. Hoffman
said that he would mainly use it when he was walking between trees, and it
would clarify his thinking. So he was the person who first introduced this to
many people, and he also said that this was a very under-researched area.
And of course, for thousands of years,
indigenous people have been using low doses of mind-altering substances as
well.
What types of people are microdosing, and who
do you think can benefit most from the practice?
Microdosing seems to improve a vast range of
conditions. I’ve explored microdosing as a safer way of doing psychedelics than
the high doses that have been used before. Roughly 95% of the people who write
me have considerable psychedelic experience. I’ll basically tell them, this
isn’t going to harm you, let me know what happens. The general response is that
they feel better. There is an actual movement towards increased health or
wellness. What that means, for instance, is that people who write in for
anxiety seem to get help with their anxiety. People who use it for learning,
improve their learning. One Ivy League student said he was using microdosing to
get through the hardest math class in the undergraduate curriculum, and he did
wonderfully in the class. Another young man used it for severe
stuttering, and others have used it for social
anxiety. One young woman, an art historian, even found that it regulated her
periods and made them painless.
What does your microdosing protocol look like?
On day one, you dose. Day two, you’re still
having the effects. Day three, you should be noticeably not having the effects,
and on day four you dose again.
For self-study, that’s ideal because it gives
you a chance to see what’s going on. After a month -which is all I ask of
people- most people say that they’re still microdosing, but not as often.
You’ve worked with hundreds of people on a
self-reported microdosing study. How did that get started and what have you
been finding?
Over the past number of years, people have
written to me and said, “I’m interested in microdosing” for this or that
reason, “can you help me?” They ask me to tell
them what I’ve been suggesting to people, and
they ask to be in the study. I then send them a protocol I’ve developed for a
self-study and ask them to get back to
me. I’ve probably sent out 200 or 300 of these,
and I’ve gotten about half as many back as reports. A number are in process
right now.
The range of interest goes from “Hey man, new
drug, cool” to “I have post-traumatic stress, I’m recovering from cancer, and I
hate my meds.” It’s a very wide range.
I get a lot of people who say “I have anxiety
or depression and I’ve either gotten off my meds or I hate my meds. Could
microdosing help?” And my response is,
“It’s helped a lot of other people and I hope
it helps you. Here’s the protocol.”
I’ve heard there’s potential for enhancing
focus and improving symptoms of ADHD, too.
What people basically say is that they’re
better. They focus more in class. A number of people have told me that it’s
like Adderall but without the side effects.
Now these people are coming off Adderall and
have used microdosing to help them taper off pharmaceuticals, or at least to
take their pharmaceutical use way, way down.
In your study, are you seeing a lot of people
turning to microdosing as a way to come off pharmaceuticals?
For some people, it can take a year or two to
come off of a pharmaceutical. A number of people have simply said that with
microdosing it was much easier. They said they could do it without incredible
suffering. A woman who was coming off of some anti-psychotics that she probably
should never have been put on said that it wasn’t that she didn’t have the same
symptoms, but she didn’t identify with them as much. She said that she could
think of her mood swings as her brain chemistry rebalancing.
“A
number of people, by the time they’ve finished a month, say, ‘I’m sleeping
better, I’m eating more healthy food, I’ve returned to yoga and I’m doing
meditation.
What’s going on beneath the surface to create
these changes?
What microdosing seems to do is rebalance
people. Here’s a generalization, which is how I’ve come to this conclusion: A
number of people, by the time they’ve finished a month, say, “I’m sleeping
better, I’m eating more healthy food, I’ve returned to yoga and I’m doing
meditation.” They’ve improved their relationship to their body ― or their
body has improved their relationship to them.
One man quit smoking. He said that he knew
smoking wasn’t good, and it was as if his body could actually help him make the
decision. What seems to happen with microdosing is that you’re more attuned to
your own real needs.
Why has there been so little research into
microdosing?
There are two main problems. One is that nobody
was interested in microdosing, even a couple of years ago. The early research
was always high-dose, and the fact that you could take psychedelics as a
microdose didn’t occur to people. The only person we knew of who microdosed
seriously was Hofmann. It was basically invisible during the time when research
was legal and most of the time when it wasn’t.
On the other side of it, I talked with a major
researcher who’s done a number of psychedelic studies and who said that he
would love to do a microdosing study.
I asked him what was stopping him. He said that
the Institutional Review Board is not going to say, “Oh you want to give a
Schedule I drug to people every few days and have them just go run around?”
It’s going to be really hard.
Now, there are two groups, one in Australia and
one in Europe, who are starting microdosing studies. I’m working with both of
those groups on designing the studies.
Aus einem Sendung:
Microdosing wird angewendet um die negative Effekte von der betreffende Droge zu minimieren.
[Dela Hoffman]
The Arndt-Schultz law:
Small doses of drugs encourage life, large doses of drugs impede life
activity, very large doses of drugs destroy life. Kotschau repeated this work
and produced the
biphasic response curve, which effectively validates the law of the
infinitesimal dose (Wilcher, 1996).
The 3rd principle: homoeopathy treat the person and not the
disease (Digby, 1996).
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